The Point-of-Care Diagnostic Landscape for Sexually Transmitted Infections (STIs)

  • Originally published on 26 October 2017
    Posted on 26 October 2017

Sexually transmitted infections (STIs) continue to be a significant global public health issue, with an estimated 357 million people becoming ill each year with one of 4 STIs: syphilis, Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Trichomonas vaginalis (TV). In addition, more than 290 million women have a human papillomavirus (HPV) infection.

This report considers the available and pipeline diagnostics for curable STIs, namely syphilis, CT, NG, TV, and HPV. With some exceptions, the existing diagnostics for these STIs are laboratory-based platforms, which typically require strong laboratory infrastructure and well-trained laboratory technicians. In addition, test turnaround time is often long, requiring patients to return for test results on a subsequent clinic visit. This, in turn, leads to significant loss to follow-up. Therefore, while these laboratory-based diagnostics are effective, they may not always be suitable for use in resource-limited settings where diagnostic access and delivery are difficult. 

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